Hodges: Would you ever bleach your hair? (Sara looks up from the microscope) I wouldn't, it's so Greg Sanders.

Jail Inmate: Yo Grissom! [hits the inmate next to him] This guy is the reason I'm in here. A shoe print! [to Grissom] Yo next time I go barefoot!
Grissom: Even better, footprints.

Janine Haywood: I told you I dropped them down the bathroom sink.
Brass: First time I heard that.
Janine Haywood: Look, I took two, gave Tony two and I accidentally dropped fifteen or twenty down the sink. It was an accident. You know, an accident? Haven't you ever spilled a drink?
Catherine: Not lately. We found fifty Xanax in Tony's stomach.
Janine Haywood: Don't pin that on me. I'd left.
Catherine: I'll tell you what you left -- your fingerprints all over the prescription bottle.
Janine Haywood: I went to the pharmacy waited in line picked up the prescription signed for it brought it back to the house. You know, Tony did nothing for himself except work and get high.
Brass: Got you a brand-new Mercedes, didn't it?
Janine Haywood: Yes, it did. And it'll buy me the dress I wear at Tony's funeral, too.
Brass: Look, when you left your half a house where did you go?
Janine Haywood: A friend's.
Brass: Well, let's get her on the line.
Janine Haywood: She's out of town.
Brass: Let me guess -- she's incommunicado.
Janine Haywood: That means you can't reach her? Yeah.

Lady Heather: I can read anyone who walks through this door and know their desires. Sometimes even before they do.

Lady Heather: It's just about knowing yourself, being strong and not taking any crap from powerful jerks who are used to giving it all day long.

Lady Heather: Unfortunately the language we speak in here doesn't necessarily translate to the world out there.
Grissom: No, in here, the submissive has the power... all he has to do is say the safety word and everything stops.
Lady Heather: Very good, Mr. Grissom.
Grissom: I'm just repeating what I've heard.
Lady Heather: You're a good listener.
Grissom: Part of the job.
Lady Heather: So, this is work?
Grissom: Yes, but I value your insight.
Lady Heather: I'm flattered...but you already seem to know the answers to your questions. You keep me in proximity when I walk away [She moves closer to him] and when I'm close you watch my lips. Are you losing your hearing?
Grissom: I'm losing my balance.
Lady Heather: Your sense of self?
Grissom: No, I know who I am.
Lady Heather: Do you?
Grissom: Yes... I do. [He touches one side of her cheek with one hand then the other with his other hand] You can always say "stop".
Lady Heather: So can you.

Lieutenant Mendez: I just made Lieutenant. I've got nothing to prove.
Catherine: A man with nothing to prove. Now that would be a first.

Lieutenant Mendez: Those the best you got? [He points over to Grissom and Catherine]
Brass: Yeah, yeah, you got lucky.
Lt. Mendez: Well, if they're not I'll fly mine in.
Brass: Let me put it to you this way - I'd want them investigating my murder.

Lt. Brooks: You don't keep any secrets, Mr. Grissom? Not even from your wife?
Grissom: [amused] I used to. I'm trying to change.

Marjorie Westcott [to Catherine]: You took your clothes off for a living.
Catherine: For a very good living.

Marjorie Westcott: [on television] Aside from the fact that the other woman in this case also known as Tonya is still at large and is still a likely suspect in this murder the evidence Las Vegas CSI did collect the evidence they're using to railroad my client, Tom Haviland, has been completely and irretrievably compromised. I'm holding in my hand compromised, contaminated evidence, ladies and gentlemen. CSI should be ashamed; and you, as citizens, should be outraged. This is not how we do things in America.

Marjorie Westcott: [to Sara] You date... you and Hank. You share a subtle communication. Did he move the bra to where you might have wanted it?
Sara: I didn't want it anywhere. I collect evidence without emotion.
Marjorie Westcott: You do get emotionally involved, though with the men on your cases. Hank Peddigrew isn't the first time.
Sara: Excuse me?
Marjorie Westcott: A murder investigation at the residence of one Charles Renteria. Eyewitness stated he saw you and your supervisor Gil Grissom standing alone outside and you were touching him in a romantic gesture.
Sara: I brushed chalk from his face.
Marjorie Westcott: Is that what they're calling it now?
Prosecutor for CSI: Objection, your honor.
Sara: Drywall dust. We were looking for a body.
Marjorie Westcott: It's a fair question, your honor. Just how far will Ms. Sidle go on the evidence to please her boss, Gil Grissom, whether he returns her attentions or not?

Marlon: Listen... I'm, uh... I'm sick. You know, I got this-this, this illness, which... look. I don't want to go back to prison. That's why I'm being so compliant. Now, yo, I don't work near no little kids. I stay a hundred yards from the school grounds. Man, I don't even go to the park.
Grissom: It's not a disease. It's a compulsion.
Marlon: I stay away from youth organizations, after-school programs, churches...
Grissom: We found a pair of boy's underwear in your bedroom. Explain that.
Marlon: I look at the photos. I look at the photos and I have the briefs for, um... release.
Grissom: So you fantasize, and eventually, the fantasy's not enough and you relapse.
Marlon: Hey, they're mine. I bought the underwear!
Grissom: Well, if that's true, then you were in a store where little children were shopping with their mothers.
Marlon: And what would you have me do, huh, man? What?! I mean, I even thought about chemical castration.
Grissom: Medroxyprogesterone is inconclusive. It renders the subject incapable of erection, but it doesn't remove the drive. You would still be capable of sexual assault using other objects.
Marlon: Listen... um, I haven't done anything, uh, illegal, so you can't hold me in here forever. Oh, is that killing look in your eyes a compulsion, Mr. Grissom?

Marty: You going to arrest me for blurring the lines?
Grissom: No. We were leaning towards murder.

Melanie Grace: My first IOLP convention -- I walk in, see 200 Dwarfs staring back at me and what goes through my head? "There's no way I look like these people." I ran.
Grissom: But you went back.
Melanie Grace: Eventually. I guess I realized it's nice to see eye-to-eye with someone.
Grissom: Mm.
Melanie Grace: I get the impression that's a little tough for you. "The freaks have looked at her in a secret way and tried to connect their eyes with hers as though to say, we know who you are. We are you."
Grissom (smiles): Faulkner.
Melanie Grace: Close. Another southern writer. Carson McCullers.
Grissom: I think we look for the differences in each other to prove that we're not alone.
Melanie Grace: What's yours? Your difference? (Grissom is silent) Mine's the worst. Random gene. Anyone can have a dwarf. Sometimes I've even seen terror in average-size people's eyes. I remind them that their little carbon copies might not be such a copy after all.
Grissom: Well, mine's genetic, progressive and impossible to predict.
Melanie Grace: And hard to notice ... unless you tell someone.