Grissom: You said that you were a doctor. May I ask your specialty?
Dr. Hillridge: Nutrition. My patients are mostly professional athletes.
Grissom: Do you ever consult with amateur athletes? Like marathoners?
Dr. Hillridge: You mean like that jogger? What was his name?
Grissom: Terry Manning.
Dr. Hillridge: Doesn't ring a bell. And I'm very good with names, Mr. Grissom. You'll let me know when I can pick up Simba.
Grissom: You're assuming a lot.
Dr. Hillridge: So are you.

Grissom: You showered.
Catherine: Thanks for noticing Gil, you're very observant.
Grissom: [studying a surveillance tape and inadvertently blocking Catherine's view]) Yeah? Well ... I can't tell what I'm observing here. What does that look like?
Catherine: A five-foot-eleven workaholic.

Grissom: You son of a bitch. You swept my crime scene. You sent cleanup!
Ecklie: I didn't send anyone. It's been on the books for months.
Grissom: So you knew, and did nothing about it even with a man's life on the line?
Ecklie: If you'd have checked the docket like everybody else you would've known what was happening. Coffee? (Ecklie holds the pot out to Grissom, Grissom hits the pot out of Ecklie's hand, it flies across the room and breaks against the door) Guess you don't want cream with that. (Ecklie leaves. Grissom notices the broken glass, and how the coffee drips on to it from the door, he makes the connection with this and the melted glass from the bedroom closet at the crime scene)
Grissom: (smiles) Thanks, Ecklie.

Grissom: You told me you weren't dating her.
Nick: I wasn't till last night after I broke up her fight with this guy, uh... Jack.
Grissom: And Ecklie's at her house now.
Nick: Yeah, and I can tell you what he's going to find. My fingerprints; my DNA.
Grissom: What were you thinking, Nicky?
Nick: I wasn't.

Grissom: You tried to save your family, but that doesn't mean that you didn't start the fire. Are you lying about that, too?
Frank: You tell me.
Grissom: I will.

Grissom: You've still got to convince a jury.
Sara: On guns. It's got to be better than bugs. Less Latin.

Grissom: You've still got to convince a jury.
Sara: On guns. It's got to be better than bugs. Less Latin.

Grissom: Your guys didn't get any extended body photos?
Brass: Chest, hands, arms right there.
Grissom: I need lower extremities for comparison.
Brass: Hey, Marjorie Westcott blew in here and shut us down. She said if we wanted full body shots we were going to have to get a court order. So the D.A.'s working on it.
Grissom: When, between testimony?
Brass: No kidding. Meanwhile, we're presenting half a case to a judge.

Grissom: [to Dr. Gerard] What happened to you? You were a pioneer in forensic science. How many bad guys did you put away in Hennepin County?
Dr. Phillip Gerard: My share. How many innocent men have been locked away since then because of sloppy investigating shortcut forensics?
Grissom: You look for mistakes in any lab, you'll find them.
Dr. Phillip Gerard: I shouldn't be able to, Gil.
Grissom: Humans are fallible.
Dr. Phillip Gerard: Not this fallible: compromised blood, sweetheart deals...
Grissom: No, no, no, no. You're subverting good evidence. These are good people.
Dr. Phillip Gerard: The accused is entitled to the best defense possible.
Grissom: The accused is entitled, yeah. He's a movie star, that's why he's entitled. He's killed two women. You know it. But you're willing to decimate these CSIs so that you can spoon-feed a jury into letting him walk.
Dr. Phillip Gerard: A jury believes me because of my reputation just like they do you.
Grissom: The difference is, Philip, I get the same paycheck regardless of what I testify to.
Dr. Phillip Gerard: I'm saying this as a friend. For the reputation of CSI, tell the D.A. to drop this, re-file down the road.
Grissom: What about the victims' families? Who's their friend? [Dr. Gerard doesn't answer] My guys will see you in court.

Grissom:(Grissom admits to a mistake) What?
Nick: Well, it's just that most people don't admit to being wrong.
Grissom: I'm wrong all the time. That's how eventually I get to "right".

Grissom:What do you do for fun?
Sara:I chase rabbits...

Henry McFadden: Paige and I dated once or twice. She wasn't my type. If you haven't noticed... I'm in the system now. The talent pool's pretty deep.
Nick: She dumped you!

Hodges: All the hairs lifted off the victim's clothes were consistent with each other. There's a sample under the scope. The root is shaped like a spade which is indicitative of canine. The scale pattern is consistent with a golden retriever.
Sara: Oh, yeah the victims have a golden retriever.
Hodges: Well if you cracked that mystery at the scene, you would have saved me a lot of time. [sighs] I've been working like a dog.
Nick: You know studies have found that pet owners have lower stress levels, you should, you should check that out.
Hodges: Well, I had a hamster when I was growing up. My mother hated them she said they stank out my room. But I just loved to watch them spinning on their little wheels. One day I came home and they were gone. Somehow they'd gotten out of their cage.
Sara: How much did your mother hate them?
Hodges: They ran away.

Hodges: Hey, I heard about court today. Must have been embarrassing, huh?
Warrick: Hodges, why'd you leave L.A. Again? Never mind, it's probably none of my business.

Hodges: How old were you when you first got drunk?
Nick: Oh, 16.. 17..
Hodges: Amortized over a generation, 12's about right?
Nick: So you're saying two generations from now, four-year-olds are just gonna be getting trashed?
Hodges: Pre-school graduation parties are going to be off the hook.