Reverse memory erasing? Now that would be science fiction.
S1 E4Francine's Flashback
My mother stole my boyfriend!
Your boyfriend stole my wife! Let's get back at them by dating each other!
[pause]
Wait a minute. Daddy didn't think that through.
[talking about euthanising a racoon] She said it was the most compassionate thing she'd ever seen.... And I got to kill something. It was a magical moment.
BPBill Pullman
Has your loved one's memory been irretrievably lost? Hi. I'm forgettable actor Bill Pullman. You might not remember me from such movies as "While You Were Sleeping" and "Twister". Wait, was I in "Twister"? No, no that was Bill Paxton. See? Memory can be pretty tricky. So that's why if you tell your loved one what's happened to them, their brain will implode. Good luck. I'm Bill Pullman. Oh, oh, I was also in Independence D... [TV turns off]
Jeff Daniels is right.
[after spraying Mace in the face of an ugly girl screaming and falling down on the floor] I know, I know, bad for the ozone
[after knocking out two girls with a frying pan] Did you see where they went?
Who?
The black guys who did this.
This midnight fishing is great.
Sounds to me like someone doesn't want to go home.
Yeah, I'm laying low. Today is the anniversary of a huge fight me and Francine got into last year.
SSStan's coworker
Yeah? What about?
Oh, I forgot our anniversary. [his coworkers look at him in realisation] I'm never gonna do that again!
CCoworker
I...
[Avery silences him. Stan takes a swig of his beer and sighs contentedly. He takes another drink... and then the penny drops]
[screams]
There it is!
S1 E5Roger Codger
[after electrocuting terrorists] I just made a killing in the shock market!
[after being thought dead and being thrown in a dumpster] Can't a guy go into a stress induced hibernation without getting thrown in the trash?
OOld lady
[spitting at the Lincoln Memorial] That's for freein' the slaves, ya Negro-lovin' Yankee Devil!
[gritting his teeth] And suddenly, things turned ugly.
Now here's your allowance: five bubbles. [blows five bubbles] Ah, what the hell--six bubbles. [blows another bubble and whispers] Don't tell your mother.
[gets in the passenger side of a car] Stan Smith, CIA! To the Smithsonian! Oh wait, this my car. [shifts over to the driver's side] Even better!
Nobody threatens my family. Now, get out of the way or I'll shoot you all.
Oh, God, it's my junior prom all over again.
Hey, Hayley, got a minute?
Roger? You're alive? Or is this like an episode of the Twilight Zone where I talk to you from beyond the grave but only with terrible ironic results?
Oh, right, it's after 12:00, you're already high. Let me talk to the fish.
[after Steve calls him a monster] I'm not a monster. [a skull pops out of the boiler. Stan kicks it back in.]
These quotes come from Wikiquote's American Dad! pages and are available under the Creative Commons Attribution-ShareAlike License.