Sheldon and Leonard in “The Desperation Emanation”

[after Amy proposed for Sheldon to meet her mother] What am I supposed to do?

Well, have you considered telling her how you feel?

Leonard, I'm a physicist, not a hippie.

All right, well, let me see if I can explain your situation using physics. What would you be if you were attached to another object by an inclined plane wrapped helically around an axis?

Screwed! [he realizes what he said]

There you go.