House and Adams in “Twenty Vicodin”

House

Before I went to Med School. Thought about getting a PHD in Physics. You ever hear of dark matter? The galaxies rotate. Motion of the universe. It means there's six times more stuff than we can detect. But it's theorized. No one's ever proved it exists.

So uh, so you want to research it? Why?

House

It's the greatest mystery there is. Theory of everything.

And completely divorced from humanity.

House

Me and humanity, we got married too young.