Dean and Sam in “Unfinished Business”

Dean

You think I'm just going to sit here like Crowley, getting all weepy while you shoot me up? Well, screw that! I don’t want this.

Sam

Yeah, I pretty much figured that out.

Dean

You don’t even know if this is going to work, do you? You know, I've got a helluva a lot more running through me than just demon juice.

Sam

Mark of Cain, got it.