Wesley, Sam and Dean and others in “Unfinished Business”

"Be careful what you wish for." You know who says that? Good looking jerks like you guys, the ones who've got it so easy because you happen to be handsome.

Easy?

Yeah. Women -- Women look at you, right? They notice you.

Sam

Believe us, we do not have it easy.

Dean

We are miserable. We never get what we want. In fact, we have to fight tooth and nail just to keep whatever it is we've got.

Sam

But you know what? Maybe that's the whole point, Wes.

Dean

Yeah, people are people 'cause they're miserable bastards, 'cause they never get what they really want.

Sam

Right, yeah, you get what you want, you get crazy.

Dean

Just take a look at Michael Jackson, hmm? Or Hasselhoff.