Tommy - Voiced by E.G. Daily.
Chuckie - Voiced by Nancy Cartwright.
Phil (Tommy's best friend) and Lil (Chuckie's girlfriend) - Voiced by Kath Soucie.
Angelica (Tommy's cousin) - Voiced by Cheryl Chase.
Dil Pickles (Tommy's younger brother) - Voiced by Tara Strong.
Susie (Phil's girlfriend) - Voiced by Cree Summer.
Kimi (Tommy's girlfriend) - Voiced by Dionne Quan.
Harold - Voiced by Pat Musick. Angelica's boyfriend.
Nicole - Voiced by Lizzy Murray in season 1 (2003-2004). Chuckie's former best friend.
Edith - Voiced by Pat Musick. Chuckie's former best friend.
Rachel (Tommy's former best friend) (who's friends with Thomanita (who was voiced by Christina Pucelli) - Voiced by Meagan Smith (2005)/Denise Pickering (2007-2008), latest appeared in "All Broke Up" as a former sidekick for Tommy.
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